Sources & evidence

Every claim, mapped to its origin

bedbugmanual.org relies on peer-reviewed studies (J Econ Entomol, Annual Review of Entomology, JAMA, Clin Microbiol Rev), agency publications (EPA, CDC, WHO, German UBA and IQWiG, Berlin-Brandenburg statistics office), and carefully evaluated trade sources. Here is the full registry, with trust level and direct links.

Total: 39 sources. Each article links inline to the source it relies on; technically the link runs as an invisible data-cite attribute in the HTML, as a Schema.org citation in the JSON-LD head, and in this central registry. The same registry backs the German sister site wanzen-weg.de.

Trust level legend

How strongly we vouch for each source, from "full PDF read and core claim verified" down to "only found via a search snippet".

LevelWhat we mean
Abstract reviewedAbstract / journal landing page read; core claim explicitly stated there
Indirectly confirmedIndirectly verified: search-engine snippet / review article repeats the exact claim
MentionTertiary source / mentioned in passing
Government / authorityOfficial German or international authority (UBA, IQWiG, statistical office, etc.)
Industry pageVendor or trade body page, commercial

Peer-reviewed studies & reviews

Original research and review articles from scientific journals, the primary evidence base for every quantitative claim.

🇺🇸 Global Perspective of Insecticide Resistance in Bed Bugs and Management Options

Lee C.Y. · 2025 · Entomological Research

Abstract reviewed
Bed bug pyrethroid resistance is now globally documented; management has shifted toward heat treatment, IPM and resistance-management combinations.
View original →DOI: 10.1111/1748-5967.70038Topic: insecticide resistance, pyrethroid resistance, global perspective, management strategieslast checked 2026-06-13

🇺🇸 Clinical manifestations of bed bug bites: A systematic review of case reports

PLOS One Systematic Review Authors (2024) · 2024 · PLOS One

Abstract reviewed
Synthesis of 64 case reports / 85 patients: pruritic erythematous maculopapules in clusters or linear/curvilinear distribution in exposed body areas. Repeated bites may cause sensitization with vesicles, urticarial wheals, bullae or systemic hypersensitivity. Local trauma can lead to secondary bacterial infection (ecthyma, cellulitis, lymphangitis).
View original →DOI: 10.1371/journal.pone.0341398Topic: bite clinical manifestations, dermatology, allergic reactions, systematic reviewlast checked 2026-06-13

🇺🇸 Historical and Contemporary Control Options Against Bed Bugs, Cimex spp.

Doggett S.L., Lee C.Y. · 2023 · Annual Review of Entomology 68:169-190

Abstract reviewed
The global resurgence of bed bugs over the past two decades is believed to be primarily due to the development of insecticide resistance, along with global travel and poor pest management.
View original →DOI: 10.1146/annurev-ento-120220-015010Topic: bed bug control options, IPM, resurgence, insecticide resistancelast checked 2026-06-13

🇺🇸 Bed Bugs, What You've Been Told is Totally False

Mark Rober mit Prof. Changlu Wang (Rutgers Urban Entomology Lab) · 2023 · YouTube

Indirectly confirmed
Diatomaceous earth: 90% bed bug mortality after 10 days. Hot Shot bed bug spray: 12% (same as water control). Pyrethroid-based foggers: no effect on field strain.
View original →Topic: diatomaceous earth 90% mortality / Hot Shot spray 12% mortality / heat treatment as 'sure-fire way'last checked 2026-06-13

🇺🇸 Detection of target-site and metabolic resistance to pyrethroids in the bed bug Cimex lectularius in Berlin, Germany

Soroka et al. · 2020 · Current Research in Parasitology & Vector-Borne Diseases

Abstract reviewed
In 14 of 17 Berlin field strains, pyrosequencing revealed the L925I substitution at allele frequencies 30-100%. One strain additionally V419L (40% males / 96% females). 5 of 7 strains showed elevated CYP397A1 mRNA (7.1 to 56-fold).
View original →Topic: Berlin pyrethroid resistance, L925I kdr mutation, V419Llast checked 2026-06-13

🇺🇸 Bed Bug Awareness Among Travelers (American Entomologist, 2017)

Potter M.F. et al., University of Kentucky · 2017 · American Entomologist

Indirectly confirmed
University of Kentucky survey on whether US travelers actually inspect hotel rooms for bed bugs. Supports the 'most travelers skip the 5-minute check' claim.
View original →Topic: survey of US traveler knowledge and inspection behavior around hotel bed bugslast checked 2026-06-13

🇺🇸 Bed bugs and possible transmission of human pathogens: a systematic review

Delaunay P. et al. · 2016 · Archives of Dermatological Research

Indirectly confirmed
Of 20 studies analyzed: 70% reported bed bugs can harbor pathogens, but only 25% demonstrated experimental transmission to animals or humans, and none to humans naturally.
View original →Topic: systematic review of bed bug pathogen carrying vs transmissionlast checked 2026-06-13

🇺🇸 A short heat treatment of luggage rapidly kills bed bugs at all life stages

Wang C., Kwan H. · 2016 · Pest Management Science / UC Irvine research

Indirectly confirmed
Wang and Kwan's heat-treatment study showing that a short, hot exposure of a packed suitcase reliably kills bed bugs at all life stages. The scientific basis for travel heat boxes.
View original →Topic: short luggage heat treatment as a bed bug travel-prevention measure, all life stageslast checked 2026-06-13

🇺🇸 Mark-Release-Recapture Reveals Extensive Movement of Bed Bugs within and between Apartments

Cooper R., Wang C., Singh N. · 2015 · PLOS ONE 10(9):e0136462

Indirectly confirmed
Bed bugs disperse within and between apartments, but inter-unit movement is limited to short distances (adjacent units, same floor).
View original →DOI: 10.1371/journal.pone.0136462Topic: bed bug movement, inter-apartment dispersallast checked 2026-06-13

🇺🇸 Accuracy of Trained Canines for Detecting Bed Bugs (Hemiptera: Cimicidae)

Cooper R., Wang C., Singh N. · 2014 · Journal of Economic Entomology 107(6):2171-2181

Indirectly confirmed
Field accuracy: mean detection rate 50% (15-77%), mean false-positive rate 32% (14-57%). 28 false positives across 11 teams; only 1 confirmed in 12-month follow-up. Handlers self-reported ≥95% accuracy.
View original →Topic: dog detection field accuracy 50%/32%last checked 2026-06-13

🇺🇸 Cold Tolerance of Bed Bugs and Practical Recommendations for Control

Olson J.F., Eaton M., Kells S.A., Morin V., Wang C. · 2013 · Journal of Economic Entomology 106(6):2433-2441

Indirectly confirmed
Achieving 100% mortality requires a minimum exposure time of 80 hours at -16°C for all life stages including eggs. Mean supercooling point ranges -21.3 to -30.3°C; LLT99 -31.2°C.
View original →DOI: 10.1603/EC13032Topic: cold tolerance, freezing protocol, 80h at -16°Clast checked 2026-06-13

🇺🇸 Bed Bugs: Clinical Relevance and Control Options

Doggett S.L., Dwyer D.E., Peñas P.F., Russell R.C. · 2012 · Clinical Microbiology Reviews 25(1):164-192

Abstract reviewed
Over 40 pathogens have been detected in bed bugs; no published study has demonstrated a causal relationship between bed bugs and infectious disease transmission to humans.
View original →DOI: 10.1128/cmr.05015-11Topic: disease transmission, pathogens, no human transmission provenlast checked 2026-06-13

🇺🇸 Temperature and Time Requirements for Controlling Bed Bugs (Cimex lectularius) under Commercial Heat Treatment Conditions

Kells S.A., Goblirsch M. · 2011 · Insects 2(3):412-422

Indirectly confirmed
100% mortality of all life stages including eggs achieved at both 50°C and 55°C under commercial heat treatment conditions.
View original →Topic: commercial heat treatment, all stages incl. eggs at 50-55°Clast checked 2026-06-13

🇺🇸 Survivorship During Starvation for Cimex lectularius L.

Polanco A.M., Brewster C.C., Miller D.M. · 2011 · Insects 2(2):232-242

Indirectly confirmed
Mean adult survival time during starvation: 41.5 to 142.6 days. First instars 13.8-36.3 days. Resistance to insecticides shortens starvation survival.
View original →Topic: starvation survival, lifespan, resistance vs susceptible strainslast checked 2026-06-13

🇺🇸 Effectiveness of Bed Bug Monitors for Detecting and Trapping Bed Bugs in Apartments

Wang C., Tsai W.T., Cooper R., White J. · 2011 · Journal of Economic Entomology 104(1):274-278

Indirectly confirmed
ClimbUp passive interceptors detected bed bugs more effectively than visual inspection in low-level infestations; over 7 days trapped similar numbers as dry-ice trap in 1 day.
View original →DOI: 10.1603/EC10269Topic: interceptor monitor effectiveness, ClimbUp, falling behaviorlast checked 2026-06-13

🇺🇸 Practical Solutions for Treating Laundry Infested with Cimex lectularius

Naylor R.A., Boase C.J. · 2010 · Journal of Economic Entomology

Indirectly confirmed
60°C wash on 30-min cycle achieves 100% mortality of all life stages. 30 min HOT dryer cycle achieves 100% mortality alone. 10-min HOT only 75-85%. 40°C wash kills adults/nymphs but only 25% of eggs.
View original →Topic: laundry, washing 60°C, dryer 30 min HOTlast checked 2026-06-13

🇺🇸 Lethal Effects of Heat and Use of Localized Heat Treatment for Control of Bed Bug Infestations

Pereira R.M., Koehler P.G., Pfiester M., Walker W. · 2009 · Journal of Economic Entomology 102(3):1182-1188

Indirectly confirmed
100% adult mortality at 41°C / 100 min or 43°C / 25 min. Adult LTime99 at 45°C = 94.8 min; eggs survived 7 h at 45°C and 71.5 min at 48°C.
View original →DOI: 10.1603/029.102.0342Topic: heat treatment, thermal death curves, adult lethal templast checked 2026-06-13

🇺🇸 Bed Bugs (Cimex lectularius) and Clinical Consequences of Their Bites

Goddard J., deShazo R. · 2009 · JAMA 301(13):1358-1366

Indirectly confirmed
No bite morphology or distribution pattern reliably distinguishes bed bug bites from other arthropod bites. Repeated infestation can cause PTSD-like symptoms.
View original →DOI: 10.1001/jama.2009.405Topic: bite clinical, no diagnostic pattern, psychological effectslast checked 2026-06-13

🇺🇸 Ability of Bed Bug-Detecting Canines to Locate Live Bed Bugs and Viable Bed Bug Eggs

Pfiester M., Koehler P.G., Pereira R.M. · 2008 · Journal of Economic Entomology 101(4):1389-1396

Indirectly confirmed
Lab trials: 97.5% positive indication rate at detecting live bed bugs with 0% false positives. Discrimination from dead bugs/cast skins/feces: 95% true positive, 3% false positive.
View original →Topic: dog detection lab accuracy 97.5%/0%last checked 2026-06-13

🇺🇸 Biology of the Bed Bugs (Cimicidae)

Reinhardt K., Siva-Jothy M.T. · 2007 · Annual Review of Entomology 52:351-374

Indirectly confirmed
Bed bugs hatch after 6 to 10 days at room temperature; saliva contains anti-coagulant nitrophorin and apyrase causing delayed bite reactions.
View original →DOI: 10.1146/annurev.ento.52.040306.133913Topic: bed bug biology, life cycle, traumatic insemination, salivary biochemistrylast checked 2026-06-13

Government & official sources

EPA, CDC, WHO, German UBA / IQWiG, statistical offices, university extension services.

🇺🇸 EPA Bed Bug Information

U.S. Environmental Protection Agency · 2025 · EPA.gov

Government / authority
Official US federal agency hub on bed bug identification, integrated pest management, and registered pesticide products.
View original →Topic: official US federal guidance on bed bug identification, IPM, registered pesticide productslast checked 2026-06-13

🇺🇸 Rutgers Urban Entomology Lab (Wang Lab)

Changlu Wang and the Rutgers Urban Entomology Lab · 2024 · entomology.rutgers.edu/labs/wang-lab

Government / authority
Primary US research group on bed bug behavior, interceptor traps, and field-tested IPM strategies, especially in multi-family housing.
View original →Topic: Rutgers research group on bed bug behavior, traps, treatment efficacy, IPM in affordable housinglast checked 2026-06-13

🇺🇸 Keep iPhone within acceptable operating temperatures (Apple Support 118431)

Apple Inc. · 2024 · Apple Support knowledge base

Government / authority
Apple's official iPhone/iPad operating (0–35°C) and storage (-20 to +45°C) temperature limits. The hard reference for 'do not put your phone in a heat chamber'.
View original →Topic: official Apple operating and storage temperature limits for iPhone and iPadlast checked 2026-06-13

🇺🇸 WHO position on bed bugs as a public health issue

World Health Organization · 2024 · WHO public statements and vector control guidance

Government / authority
WHO classifies bed bugs as a nuisance pest without proven human disease transmission; advice is hygiene-agnostic and travel-related.
View original →Topic: international public-health stance on bed bugs as nuisance pest, no proven human disease transmissionlast checked 2026-06-13

🇺🇸 Bed Bugs (Texas A&M AgriLife / Citybugs)

Texas A&M AgriLife Extension, Department of Entomology · 2024 · citybugs.tamu.edu

Government / authority
Texas A&M extension fact sheets; a workmanlike complement to Penn State and University of Kentucky as a US university reference.
View original →Topic: university extension service fact sheet on bed bug biology and managementlast checked 2026-06-13

🇺🇸 Bed Bugs (Penn State Extension fact sheet)

Penn State Extension, Department of Entomology · 2024 · extension.psu.edu

Government / authority
Comprehensive homeowner-facing IPM and identification guide from the Penn State entomology department, one of the standard US extension references.
View original →Topic: homeowner-facing identification, biology, IPM, treatment, university extension servicelast checked 2026-06-13

🇺🇸 Inspecting for bed bugs (MSU Extension)

Michigan State University Extension · 2024 · canr.msu.edu

Government / authority
Step-by-step inspection protocol for bed bugs in beds and adjacent furniture, a complement to Penn State Extension.
View original →Topic: step-by-step inspection protocol for bed bugs in beds and adjacent furniturelast checked 2026-06-13

🇺🇸 Bedbugs and travel (Health Canada)

Health Canada / Public Health Agency of Canada · 2024 · canada.ca

Government / authority
Federal Canadian travel guidance on bed bug prevention with practical checklists, often crisper than the equivalent EPA pages.
View original →Topic: Canadian federal travel-prevention guidance for bed bugslast checked 2026-06-13

🇺🇸 Bedbug bites (MedlinePlus medical encyclopedia)

National Library of Medicine / MedlinePlus · 2024 · MedlinePlus.gov

Government / authority
Patient-facing reference on bite presentation, self-care, and when medical attention is warranted, from the US National Library of Medicine.
View original →Topic: clinical management of bed bug bites, when to see a doctor, common bite presentationslast checked 2026-06-13

🇺🇸 Bed Bugs (Northeastern IPM Center)

Northeastern IPM Center · 2024 · neipmc.org

Government / authority
Regional IPM consortium covering university and government bed bug guidance in the US Northeast, with traveler-focused materials.
View original →Topic: regional IPM center for bed bugs in the US Northeast, traveler and housing guidancelast checked 2026-06-13

🇺🇸 CDC Bed Bug FAQs and Health Information

U.S. Centers for Disease Control and Prevention · 2024 · CDC.gov

Government / authority
Public-health framing from the US CDC: confirms no human disease transmission, plus bite reaction guidance for clinicians and the public.
View original →Topic: public-health guidance on bed bug bites, disease transmission status, no human pathogen vectorlast checked 2026-06-13

Industry, press, other references

Trade pages, journalism, vendor documentation, context only, not primary evidence.

🇺🇸 NESDCA (National Entomology Scent Detection Canine Association)

NESDCA · 2024 · nesdca.com

Industry page
US certification body for bed bug detection dog teams. The reference point for handler-dog quality benchmarks in North America.
View original →Topic: US certification body for scent-detection dogs used in bed bug inspectionlast checked 2026-06-13

🇺🇸 Bed bugs in electronics (Brampton Pest Control)

Brampton Pest Control · 2024 · bramptonpestcontrol.ca

Industry page
Canadian commercial pest-control blog. We use it only for anecdotes about where bed bugs hide in electronics; not a primary source.
View original →Topic: industry blog post on bed bugs hiding in electronics and laptopslast checked 2026-06-13

🇺🇸 iPhone Overheating Troubleshooting (iFixit)

iFixit community · 2024 · iFixit.com

Industry page
Third-party documentation of iPhone thermal sensors and graduated response (display dim, charging stop, warning, shutdown). Source for the 40/50/60°C thresholds Apple does not publish.
View original →Topic: third-party documentation of iPhone thermal sensors and graduated thermal response thresholdslast checked 2026-06-13

🇺🇸 National Pest Management Association (NPMA / PestWorld) bed bug survey data

NPMA · 2024 · pestworld.org

Industry page
US trade association surveys of pest management professionals on bed bug encounter rates. Useful industry-side data, with the usual industry self-interest caveat.
View original →Topic: US pest control trade body surveys on bed bug encounters by pest management professionalslast checked 2026-06-13

🇺🇸 Bed Bug Foundation (UK / international)

The Bed Bug Foundation · 2024 · bedbugfoundation.org

Industry page
International non-profit promoting best-practice bed bug management in the hospitality sector. Practical hospitality framing rather than primary research.
View original →Topic: international non-profit pushing best-practice bed bug management standards in hospitalitylast checked 2026-06-13

🇺🇸 LCD Temperature Range (Orient Display knowledge base)

Orient Display engineering team · 2024 · orientdisplay.com

Industry page
Display manufacturer documentation of LCD operating range, storage range, and failure modes (ghosting, dead pixels) under cold and heat. The technical backing for our freezer claims.
View original →Topic: manufacturer-side documentation of LCD operating, storage, and damage temperature rangeslast checked 2026-06-13

🇺🇸 iPhone temperature warning thresholds (componentidigitali analysis)

componentidigitali (third-party repair documentation) · 2023 · componentidigitali

Industry page
Third-party repair-side documentation of iPhone thermal thresholds (40/50/60°C tiered responses). Explicitly flagged as not an official Apple specification.
View original →Topic: third-party reverse-engineering of iPhone thermal warning and shutdown thresholds (40/50/60°C)last checked 2026-06-13

🇺🇸 Bedbugregistry.com (US user-submitted hotel infestation reports)

Bedbugregistry.com · 2006 · bedbugregistry.com (US online directory)

Deprecated 2026-06-13Mention

Why we no longer cite this: Site has been largely dormant since around 2018 (most city pages have no recent user reports). Older travel articles still link to it. We do not cite it inline; we keep this entry visible on /sources so readers who saw it referenced elsewhere can see why we no longer treat it as a live signal. Recent TripAdvisor / Google reviews of the property are the better current alternative.

Crowdsourced US registry of hotel bed bug reports, largely dormant since around 2018.
View original →Topic: US hotel and apartment bed bug user-submitted reports (deprecated)last checked 2026-06-13

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